Turning Experience Into Discovery

  • Our work spans clinical studies, translational science, and community initiatives. Every patient we treat fuels new discoveries that shape the future of thyroid, parathyroid, and adrenal care.

    Thyroid → Cancer biology and recurrence, community screening, precision and robotic surgery.

    Parathyroid → Bone and metabolic health (osteoporosis, muscle wasting, hair loss), advanced imaging, and re-operative outcomes.

    Adrenal → Minimally invasive and function-preserving surgery, genetics of primary aldosteronism and Cushing’s syndrome, pheochromocytoma, and adrenal cancer genomics.

    • Innovations in surgery → minimally invasive adrenalectomy, function-preserving adrenal surgery, robotic thyroidectomy, and advanced imaging for parathyroid localization.

    • Community research → free thyroid ultrasound screenings and awareness campaigns to improve early detection.

    • Genetic & molecular studies → genomic drivers of pheochromocytoma and adrenal cancer (e.g., CACNA1H, ACC mutations), adrenal tumor biology (PRKACA), and thyroid/parathyroid tumor pathways.

    • Clinical outcomes research → long-term cure rates, re-operative thyroid and parathyroid surgery, and the impact of high-volume endocrine surgery on preventing avoidable re-operations.

    • Genomics & epigenetics → discovering the genetic and molecular pathways behind endocrine tumors, including whole-exome and whole-genome approaches.

    • Precision medicine → tailoring surgical and medical treatments based on tumor biology, genetic drivers, and individual patient factors.

    • Bone & metabolic health → exploring how parathyroid disease impacts osteoporosis, muscle wasting, and hair loss, with implications for quality of life.

    • International collaborations → joint studies with leading universities (Athens, Charité Berlin, Karolinska, Stockholm) and industry partners (Mimedix and others).

    • Expanding research scope → manuscripts in preparation on Cushing’s syndrome, primary aldosteronism pathways, and function-preserving adrenal surgery.

Julie Canan Julie Canan

A Rare Case of Parathyroid Cancer

Parathyroid cancer is already one of the rarest cancers, and cases where the tumor doesn’t produce excess hormone are even more unusual. This report highlights the challenges of diagnosing and treating such a “nonfunctional” parathyroid carcinoma, underscoring the importance of expert surgical care and ongoing research to better recognize and manage these rare cases.

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Julie Canan Julie Canan

Redefining Scarless Thyroid Surgery in the U.S.

Dr. Eyas Alkhalili and colleagues reported the first U.S. case series using the da Vinci Single-Port robotic system for transaxillary thyroidectomy—achieving precise surgery with no neck scar, faster recovery, and outstanding safety outcomes.

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Julie Canan Julie Canan

Redefining Adrenal Surgery: Safer, Faster, More Personalized

Adrenal surgery has entered a new era. Instead of large incisions and long recoveries, today’s patients benefit from minimally invasive techniques that are safer, faster, and often preserve part of the adrenal gland—helping them avoid lifelong medications.

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Julie Canan Julie Canan

New Genetic Insights: CACNA1H’s Role in Pheochromocytoma

A new genetic study has identified rare variants in the CACNA1H gene and found that this gene is consistently less active in pheochromocytoma tumors. These insights shed light on how adrenal tumors develop and may point to future diagnostic and treatment options.

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Julie Canan Julie Canan

Genomic Insights Into Adrenal Cancer and Patient Survival

A large, international study of more than 160 patients with adrenal cortical carcinoma has revealed 461 genes whose expression levels align closely with survival — and identified 45 genes whose mutations are independently associated with worse outcomes. These findings may open doors to better diagnostics and personalized therapies for this aggressive cancer.

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Julie Canan Julie Canan

Protecting the Voice Nerve During Thyroid Surgery

Thyroid surgery sometimes injures the recurrent laryngeal nerve, causing temporary voice problems. This study shows that placing a human amnion/chorion membrane over the nerve during surgery may greatly reduce the risk and speed recovery.

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Julie Canan Julie Canan

Unmasking Normocalcemic Hyperparathyroidism

Sometimes parathyroid disease doesn’t show up with high calcium levels, making it harder to spot. This condition, called normocalcemic hyperparathyroidism, can still cause bone loss, kidney issues, and other symptoms. Research is helping doctors understand these hidden cases—so patients can get answers and treatment sooner, even when blood calcium appears “normal.”

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Julie Canan Julie Canan

Smaller, Smarter Surgery for Parathyroid Disease

This study shows that in most cases of primary hyperparathyroidism, a focused, minimally invasive operation is just as effective as traditional four-gland dissection—avoiding bigger surgeries without sacrificing cure rates.

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Julie Canan Julie Canan

Vitamin D and Safer Thyroid Surgery

This study explored whether low vitamin D levels before thyroid surgery increase the risk of low calcium afterwards. The findings help refine how doctors prepare patients for surgery to improve safety and recovery.

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